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Clinical interpretation: when is a variant a mutation?
Genome sequencing produces volumes of valuable data, but what are the challenges of interpretation that gives practitioners the answers they need?
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Using genomics to fight infectious diseases
As genomics becomes increasingly relevant in clinical practice, it could help tackle outbreaks of diseases such as tuberculosis and measles
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Psychiatric genomics - a double-edged sword?
While genomics alone may not generate a diagnosis or wide-scale treatment, it may help us better understand psychiatric disorders
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Genomics and the trouble with 'N of 1' trials
Randomised controlled trials are a rigorous way to identify cause and effect, but when it comes to rare genomic variants, connections can be hard to detect
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Finding needles in haystacks: making sense of genomic data
Sequencing the genome is just the start; interpreting the sequence is the next big challenge
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Destined for fitness? The genetic influences on exercise
Studies have identified genes that can influence a person's exercise performance and response, as well as their propensity for injury
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Novel 'virotherapy' shows promise for skin cancer treatment
Modified virus known as T-vec mounts dual attack on cancer cells
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Sequencing cancer DNA - what are the issues?
Whole genome sequencing can reveal vast amounts about how cancer cells work, but the process of discovery is not without challenges
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How to handle hospital-acquired infections with genomics
Technology used to analyse the human genome can be applied to infective agents to identify and track the outbreak
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Precision in medicine in action
Genomics can help to target treatments for patients with cancer, rare inherited conditions, and infectious diseases
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Unexpected genomic findings: who wants to know?
A ground-breaking survey on health professionals, researchers and the public's attitudes towards genomics raises some important questions
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Gene therapy moves towards the mainstream
While still in their infancy, gene therapy techniques could hold great promise for patients with rare diseases