![Visualisation of a genome sequence as a tunnel](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/04/Sequencing-tunnel_1350x450-450x150.jpg)
Looking back: genomics in 2021
As we approach the end of 2021, we look back on the key developments in genomics and their impact on healthcare and society
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100,000 Genomes Project 2021 update: rare disease
How has rare disease diagnosis and treatment improved in light of data gathered from the 100,000 Genomes Project? Find out in the second part of our series…
![Interpretation of genomic data surrounded by circular screens](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/12/sequencing-circle-1350x450-450x150.png)
100,000 Genomes Project 2021 update: cancer
In the first instalment of a two-part series, we look at how the 100,000 Genomes Project continues to impact cancer care
![](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2020/07/Mito_1350x450-450x150.jpg)
Diagnosing mitochondrial conditions: a WGS breakthrough
Mitochondrial conditions can be difficult to diagnose – but why, and how can genomic technology help?
![Crowd of people making the shape of two kidneys viewed from above](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/12/Kidney-people_1350x450-01-450x150.png)
Polycystic kidney disease and genomic testing
We explore genomics’ role in the cause, diagnosis and treatment of a complex kidney condition
![Artistic interpretation of a neanderthal male walking towards a modern day male with a DNA helix in the background](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/11/Neanderthal-modern_1350x450-450x150.png)
Covid-19 'neanderthal' gene variants explained
In light of new research, we revisit the role our genome plays in the severity of Covid-19 symptoms
![Red blood cells in bloodstream](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/11/Redbloodcells_1350x450-450x150.png)
NICE approves RNAi therapy for porphyria
This week, we look at the latest gene silencing treatment approved by NICE – this time for an acute form of porphyria
![3D render of a chain of molecule](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/11/3D-Molecule_1350x450-450x150.png)
Reading DNA - where to start?
This week, we learn all about directionality in DNA and why it matters
![](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/11/Test-tube-DNA_1350x450-450x150.jpg)
World-first study shows WGS improves diagnostic journey
Impressive results make the case for the adoption of whole genome sequencing as "the genetic test of choice for rare disease patients"
![Illustration of a kidney and blood pressure monitor being investigated by a doctor.](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/11/Hypertension-aldosterone_1350x450-450x150.png)
Genes, hormones and blood pressure
This week, we explore genomics’ role in primary aldosteronism – a hormone disorder that leads to high blood pressure
![Many icons representing Covid-19 and a large circle containing an icon representing a DNA helix](http://www.genomicseducation.hee.nhs.uk/wp-content/uploads/2021/10/Covid-genomes_1350x450-450x150.png)
Sequencing Covid-19: 1 million genomes
As the UK reaches a mega sequencing milestone, we look at how the data could be used to better prepare us for the future
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GEP fellow publishes RNA splicing study
Jamie Ellingford and his co-authors explore the potential of computational tools to help us learn more about the messages our genes create