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Genomics in Pathology

At a Glance

Up to 6 weeks
Accredited
Part Time
CPPD (15 credits)
Blended learning

Molecular Pathology of Cancer and Application in Diagnosis, Screening and Treatment

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This course provides detailed knowledge and understanding of the molecular mechanisms involved in cancer development, including how interrogation of a person’s own genome and the genome of tumour cells can facilitate the diagnosis and personalised treatment of cancer.

This module forms part of the HEE Genomics Education Programme’s Master’s in Genomic Medicine framework.

Description

During this course, you will explore the molecular mechanisms that underlie cancer development, growth and metastasis, the differences between various cancers, as well as the different molecular and cellular actions of anti-cancer treatments. You will discover the genomic factors affecting response and resistance to treatment and the research approaches to anti-cancer drug design and development. And you will discuss the factors that lead to a person and/or their family having a higher risk of developing cancer, how this genomic information can be integrated into cancer screening programmes and the impact this may have.

This module will also help you to interrogate the cancer data sets from the 100,000 Genomes Project if relevant to the research project you need to complete as part of the Master’s programme.

Learn from leading experts in genomics about:

  • Cellular properties of tumours: growth, division, invasion, aberrant hormone or toxin production, immunogenicity including T cell and B cell repertoire profiling.
  • Tumour classification systems and factors in tumour formation.
  • Diagnosis, molecular sub-classification and characterisation of metastases.
  • Breakthrough tumour /metastases and molecular mechanisms.
  • Genomic testing of solid tumours and haematological cancers.
  • Analytical and interpretation challenges in genomics as applied to cancer.
  • Genomic and cellular markers and optimal treatment regimes in haematological cancer and solid tumours.
  • Monitoring disease following treatment.
  • Molecular basis of germline mutations for cancer predisposition.
  • Approaches in identifying new genes.
  • Situations that create a high cancer risk for a person or members of a person’s family.
  • Role of genomics in drug development and the role of clinical trials in treatment options.

Learning outcomes

By the end of this module you will be able to:

  • Analyse the molecular and cellular processes leading to cancer development and emerging changes in tumour classification.
  • Appraise the genomic basis of cancer predisposition and understand how this is used to identify people and families at higher risk of cancer.
  • Critically evaluate how genomic information is applied in the diagnosis, classification, prognosis, treatment selection, and monitoring of cancer.
  • Analyse how genome analysis of neoplastic cells and RNA sequencing data can be used to investigate the molecular and cellular processes leading to cancer development and inform strategies for drug development.

Funding rules

The Genomics Education Programme offers funding on a modular basis, initially covering 1-4 modules, with the potential for additional funding for the full Master’s degree upon demonstrating satisfactory progress. The maximum amount of funding available to each student is the equivalent of 12 modules (180 credits), to cover the full Master’s degree.

Funding covers course fees only and is limited to NHS healthcare professionals working in England on a permanent contract from the full range of professional backgrounds and groups (such as medicine, nursing, healthcare scientists and technologists). Please note funding can only be allocated to those who are post registration professionals.

University entry requirements may include criteria around existing understanding and minimum English language requirements.

The Genomics Education Programme provides limited funding to the Universities listed below. Please check with your preferred university to obtain details of the programme modules and entry criteria.

More information about the application process for CPPD module(s)/PGCert or PGDip/Master’s applications is available on this webpage.

Timetable

  Start date  
Imperial College London TBC
Queen Mary University of London / University College London TBC
St George’s, University of London / King’s College London 19th February 2025
University of Birmingham TBC
University of Cambridge 03rd February 2025
University of Exeter TBC
University of Manchester TBC

Please check your preferred university’s website for more detailed information about start dates, length and mode of study.

 

FAQs

Are applications for funding still open during the Covid-19 pandemic?

Yes. Many of our partner universities are running modules online and funding is available. Please contact your chosen university to discuss your options. You must meet the Health Education England Genomics Education Programme eligibility criteria to receive funding for modules.

I have previously applied and received funding for two modules, but would like to complete two more. Is it possible to transfer my studies to another university?

Yes.  You will need to speak to your chosen university re your requirements. You must also meet the HEE GEP eligibility criteria for funding.

I have previously applied and received funding for two modules, but would like to complete two more. Is it possible to obtain funding?

Yes.  You will need to speak to your chosen university re your requirements. You must also meet the HEE GEP eligibility criteria for funding

I have been awarded funding and started the programme, but I am unable to complete. What are my options?

Funding is awarded for the period specified in the application form and there is no automatic ability to defer completion of the programme. You should speak to your university in the first instance about your situation and also contact the Genomics Education Programme (GEP) team regarding funding.

You may choose to reduce the workload of your programme by switching from, for example, a full Master’s degree to a diploma or certificate. Again, you would need to contact your course provider and the GEP.

How much study time is required to undertake this programme?

Study time will vary across the course providers. You are advised to visit your preferred university’s website for more information or to contact the relevant course lead. Most modules involve around 5 days of face-to-face teaching, followed by 2-4 weeks of independent study and assessment preparation. However, distance learning options are available for most universities.

 

Can I build up my CPPD modules to a full Master’s, PGDip or PGCert qualification?

Funding is allocated on an individual module basis only. Candidates who meet the HEE Genomics Education Programme eligibility criteria for funding can apply for up to four funded modules in the first instance. If you wish to progress to a full Master’s or PGDip, you should discuss options with your chosen university.

I am eligible but have been refused a commissioned place – why?

This may be due to the following potential reasons:

  • The university you have applied to has used up all its commissioned allocations.
  • The total number of available national commissions have been fully allocated.
  • We are now applying controls to the commissioned places based on healthcare profession roles to help ensure equitable access across professions on a national scale.

I am not eligible for a HEE-funded place – can I self-fund?

This should be discussed with your preferred university.

I work for an organisation that provides services to the NHS – am I eligible to apply?

Yes – please provide details of your organisation and its services for the NHS when you apply to your preferred university.

Make an enquiry

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University Providers

Funded

The logos below indicate the university providers that are able to accept HEE funded applications for this course. Follow the links provided to begin your university application process.

Imperial College LondonQueen Marys University of London / University College LondonSt Georges, University of LondonUniversity of BirminghamUniversity of CambridgeUniversity of ExeterUniversity of Manchester

Self Funded

The logos below indicate the university providers that may be able to accept self-funded applications for this course. Follow the links provided to begin your university application process.

The University of SheffieldUniversity of Southampton

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